Coding
Part:BBa_K1394002:Design
Designed by: Sean Lowe Group: iGEM14_Melbourne (2014-10-05)
MAP star peptide
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal AgeI site found at 336
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
The protein was designed to both be highly soluble and lacking sequences which would make it prone to proteolytic degradation.
Source
The peptide is completely synthetic and was designed by the University of Melbourne iGEM team. It is expressed with the fusion partner, SUMO, to improve solubility. The SUMO protein sequence was derived from the work of TU Delft 2013 iGEM. The DNA sequence for this protein was codon optimised for E. coli.